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Chemoresistance in the Human Triple-Negative Breast Cancer Cell Line MDA-MB-231 Induced by Doxorubicin Gradient Is Associated with Epigenetic Alterations in Histone Deacetylase

Chemoresistance is one of the major causes of therapeutic failure in breast cancer patients. In this study, the mechanism of chemoresistance in human triple-negative breast cancer (TNBC) cells (MDA-MB-231) induced by doxorubicin (DOX) gradient was investigated. These DOX-resistant cells showed highe...

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Detalles Bibliográficos
Autores principales:	Han, Jeonghun, Lim, Wanyoung, You, Daeun, Jeong, Yisun, Kim, Sangmin, Lee, Jeong Eon, Shin, Tae Hwan, Lee, Gwang, Park, Sungsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582875/ https://www.ncbi.nlm.nih.gov/pubmed/31275376 http://dx.doi.org/10.1155/2019/1345026

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