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FCGR3A and FCGR2A Genotypes Differentially Impact Allograft Rejection and Patients' Survival After Lung Transplant

Fc gamma receptors (FcγRs) play a major role in the regulation of humoral immune responses. Single-nucleotide polymorphisms (SNPs) of FCGR2A and FCGR3A can impact the expression level, IgG affinity and function of the CD32 and CD16 FcγRs in response to their engagement by the Fc fragment of IgG. The...

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Detalles Bibliográficos
Autores principales:	Paul, Pascale, Pedini, Pascal, Lyonnet, Luc, Di Cristofaro, Julie, Loundou, Anderson, Pelardy, Mathieu, Basire, Agnes, Dignat-George, Françoise, Chiaroni, Jacques, Thomas, Pascal, Reynaud-Gaubert, Martine, Picard, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582937/ https://www.ncbi.nlm.nih.gov/pubmed/31249568 http://dx.doi.org/10.3389/fimmu.2019.01208

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