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Hypo-Osmotic-Like Stress Underlies General Cellular Defects of Aneuploidy
Aneuploidy, referring to unbalanced chromosome numbers, represents a class of genetic variation associated with cancer, birth defects and eukaryotic microbes(1–4). Whereas it is known that each aneuploid chromosome stoichiometry can give rise to a distinct pattern of gene expression and phenotypic p...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583789/ https://www.ncbi.nlm.nih.gov/pubmed/31068692 http://dx.doi.org/10.1038/s41586-019-1187-2 |