Analysis of inflammatory and metabolic biomarkers in patients submitted to abdominoplasty after bariatric surgery

PURPOSE: To evaluate the serum variations of Interleukins (Il) and CPR of abdominoplasties in post-bariatric patients and, to equate the homeostasis (HOMA) from the variations of glycemia and insulin to evolute the metabolic modifications. METHODS: Fourteen women were submitted to abdominoplasties with weight loss after a gastroplasty. Levels of IL(4), IL(6), IL(10), CRP, glycemia and insulin were obtained during the pre-operative, trans-operative, 24 hours post, 7(th) and 14(th) postoperative days. RESULTS: The IL(4) was higher at 24 hours post-surgery, and after a moderate decrease, it remained high until the 14(th) day. The IL(6) and CRP had an expressive increase during the trans-operative period. The CRP remained high, and the IL(6) decreased on the 7(th) and 14(th) days. The IL(10) increased during the transoperative period, and it posteriorly decreased to lower levels in comparison to the pre-operative period. The already increased glycemia during the pre-operative period was even higher during the trans-operative and then, returned to preliminary values on the 7(th) and 14(th) days after surgery. The HOMA accompanied the insulin. CONCLUSION: The inflammatory and glycemic serum levels decrease after abdominiplasty in obese post-bariatric patients.