Synthetic bovine NK-lysin-derived peptide (bNK2A) does not require intra-chain disulfide bonds for bactericidal activity

Bovine NK-lysins are cationic antimicrobial proteins found predominantly in the cytosolic granules of T lymphocytes and NK-cells. NK-lysin-derived peptides show antimicrobial activity against both Gram positive and Gram negative bacteria. Mature NK-lysin protein has six well-conserved cysteine resid...

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Detalles Bibliográficos
Autores principales: Dassanayake, Rohana P., Falkenberg, Shollie M., Nicholson, Eric M., Briggs, Robert E., Tatum, Fred M., Sharma, Vijay K., Reinhardt, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583974/
https://www.ncbi.nlm.nih.gov/pubmed/31216348
http://dx.doi.org/10.1371/journal.pone.0218507

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