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mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans
J. Christian Pérez studies the interplay between Candida albicans and the mammalian host. In this mSphere of Influence article, he reflects on how “Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity” (S. M. Noble, S. French, L. A....
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Microbiology
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584370/ https://www.ncbi.nlm.nih.gov/pubmed/31217300 http://dx.doi.org/10.1128/mSphere.00258-19 |
| _version_ | 1783428504123080704 |
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| author | Pérez, J. Christian |
| author_facet | Pérez, J. Christian |
| author_sort | Pérez, J. Christian |
| collection | PubMed |
| description | J. Christian Pérez studies the interplay between Candida albicans and the mammalian host. In this mSphere of Influence article, he reflects on how “Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity” (S. M. Noble, S. French, L. A. Kohn, V. Chen, et al., Nat Genet 42:590–598, 2010, https://doi.org/10.1038/ng.605) provided tools and a blueprint for open-ended genetic screens in an organism that had been a challenge for genetic manipulation. |
| format | Online Article Text |
| id | pubmed-6584370 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | American Society for Microbiology |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-65843702019-06-20 mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans Pérez, J. Christian mSphere Commentary J. Christian Pérez studies the interplay between Candida albicans and the mammalian host. In this mSphere of Influence article, he reflects on how “Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity” (S. M. Noble, S. French, L. A. Kohn, V. Chen, et al., Nat Genet 42:590–598, 2010, https://doi.org/10.1038/ng.605) provided tools and a blueprint for open-ended genetic screens in an organism that had been a challenge for genetic manipulation. American Society for Microbiology 2019-06-19 /pmc/articles/PMC6584370/ /pubmed/31217300 http://dx.doi.org/10.1128/mSphere.00258-19 Text en Copyright © 2019 Pérez. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) . |
| spellingShingle | Commentary Pérez, J. Christian mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans |
| title | mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans |
| title_full | mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans |
| title_fullStr | mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans |
| title_full_unstemmed | mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans |
| title_short | mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans |
| title_sort | msphere of influence: a systematic approach to dissect virulence traits in candida albicans |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584370/ https://www.ncbi.nlm.nih.gov/pubmed/31217300 http://dx.doi.org/10.1128/mSphere.00258-19 |
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