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The human NMDA receptor GluN2A(N615K) variant influences channel blocker potency

N‐methyl‐D‐aspartate (NMDA) receptors are glutamate receptors with key roles in synaptic plasticity, due in part to their Mg(2+) mediated voltage‐dependence. A large number of genetic variants affecting NMDA receptor subunits have been found in people with a range of neurodevelopmental disorders, in...

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Detalles Bibliográficos
Autores principales:	Marwick, Katie F. M., Skehel, Paul A., Hardingham, Giles E., Wyllie, David J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584472/ https://www.ncbi.nlm.nih.gov/pubmed/31249692 http://dx.doi.org/10.1002/prp2.495

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