Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade

Neoantigens (nAgs) are promising tumor antigens for cancer vaccination with the potential of inducing robust and selective T cell responses. Genetic vaccines based on Adenoviruses derived from non-human Great Apes (GAd) elicit strong and effective T cell-mediated immunity in humans. Here, we investi...

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Detalles Bibliográficos
Autores principales: D’Alise, Anna Morena, Leoni, Guido, Cotugno, Gabriella, Troise, Fulvia, Langone, Francesca, Fichera, Imma, De Lucia, Maria, Avalle, Lidia, Vitale, Rosa, Leuzzi, Adriano, Bignone, Veronica, Di Matteo, Elena, Tucci, Fabio Giovanni, Poli, Valeria, Lahm, Armin, Catanese, Maria Teresa, Folgori, Antonella, Colloca, Stefano, Nicosia, Alfredo, Scarselli, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584502/
https://www.ncbi.nlm.nih.gov/pubmed/31217437
http://dx.doi.org/10.1038/s41467-019-10594-2

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