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Analysis and remedy of negativity problem in hybrid stochastic simulation algorithm and its application
BACKGROUND: The hybrid stochastic simulation algorithm, proposed by Haseltine and Rawlings (HR), is a combination of differential equations for traditional deterministic models and Gillespie’s algorithm (SSA) for stochastic models. The HR hybrid method can significantly improve the efficiency of sto...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584509/ https://www.ncbi.nlm.nih.gov/pubmed/31216983 http://dx.doi.org/10.1186/s12859-019-2836-z |