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Network-based prediction of polygenic disease genes involved in cell motility

BACKGROUND: Schizophrenia and autism are examples of polygenic diseases caused by a multitude of genetic variants, many of which are still poorly understood. Recently, both diseases have been associated with disrupted neuron motility and migration patterns, suggesting that aberrant cell motility is...

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Detalles Bibliográficos
Autores principales: Bern, Miriam, King, Alexander, Applewhite, Derek A., Ritz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584515/
https://www.ncbi.nlm.nih.gov/pubmed/31216978
http://dx.doi.org/10.1186/s12859-019-2834-1

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