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Network-based prediction of polygenic disease genes involved in cell motility
BACKGROUND: Schizophrenia and autism are examples of polygenic diseases caused by a multitude of genetic variants, many of which are still poorly understood. Recently, both diseases have been associated with disrupted neuron motility and migration patterns, suggesting that aberrant cell motility is...
Autores principales: | Bern, Miriam, King, Alexander, Applewhite, Derek A., Ritz, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584515/ https://www.ncbi.nlm.nih.gov/pubmed/31216978 http://dx.doi.org/10.1186/s12859-019-2834-1 |
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