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Environmental microcystin targets the microbiome and increases the risk of intestinal inflammatory pathology via NOX2 in underlying murine model of Nonalcoholic Fatty Liver Disease

With increased climate change pressures likely to influence harmful algal blooms, exposure to microcystin, a known hepatotoxin and a byproduct of cyanobacterial blooms can be a risk factor for NAFLD associated comorbidities. Using both in vivo and in vitro experiments we show that microcystin exposu...

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Detalles Bibliográficos
Autores principales: Sarkar, Sutapa, Kimono, Diana, Albadrani, Muayad, Seth, Ratanesh K., Busbee, Philip, Alghetaa, Hasan, Porter, Dwayne E., Scott, Geoff I., Brooks, Bryan, Nagarkatti, Mitzi, Nagarkatti, Prakash, Chatterjee, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584534/
https://www.ncbi.nlm.nih.gov/pubmed/31217465
http://dx.doi.org/10.1038/s41598-019-45009-1