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Environmental microcystin targets the microbiome and increases the risk of intestinal inflammatory pathology via NOX2 in underlying murine model of Nonalcoholic Fatty Liver Disease
With increased climate change pressures likely to influence harmful algal blooms, exposure to microcystin, a known hepatotoxin and a byproduct of cyanobacterial blooms can be a risk factor for NAFLD associated comorbidities. Using both in vivo and in vitro experiments we show that microcystin exposu...
Autores principales: | Sarkar, Sutapa, Kimono, Diana, Albadrani, Muayad, Seth, Ratanesh K., Busbee, Philip, Alghetaa, Hasan, Porter, Dwayne E., Scott, Geoff I., Brooks, Bryan, Nagarkatti, Mitzi, Nagarkatti, Prakash, Chatterjee, Saurabh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584534/ https://www.ncbi.nlm.nih.gov/pubmed/31217465 http://dx.doi.org/10.1038/s41598-019-45009-1 |
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