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Energetic, Structural and Dynamic Properties of Nucleobase-Urea Interactions that Aid in Urea Assisted RNA Unfolding

Understanding the structure-function relationships of RNA has become increasingly important given the realization of its functional role in various cellular processes. Chemical denaturation of RNA by urea has been shown to be beneficial in investigating RNA stability and folding. Elucidation of the...

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Detalles Bibliográficos
Autores principales: Jaganade, Tanashree, Chattopadhyay, Aditya, Pazhayam, Nila M., Priyakumar, U. Deva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584539/
https://www.ncbi.nlm.nih.gov/pubmed/31217494
http://dx.doi.org/10.1038/s41598-019-45010-8

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