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PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1

Most deaths from breast cancer result from tumour recurrence, which is typically an incurable disease. Down-regulation of the pro-apoptotic tumour suppressor protein prostate apoptosis response-4 (PAR-4) is required for breast cancer recurrence and resistance to chemotherapy. Recent advances in the...

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Detalles Bibliográficos
Autores principales:	Guo, Haihong, Treude, Fabian, Krämer, Oliver H., Lüscher, Bernhard, Hartkamp, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584570/ https://www.ncbi.nlm.nih.gov/pubmed/31217499 http://dx.doi.org/10.1038/s41598-019-45209-9

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