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Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration

We previously used a chemical genetics approach with the larval zebrafish to identify small molecule inhibitors of tissue regeneration. This led to the discovery that glucocorticoids (GC) block early stages of tissue regeneration by the inappropriate activation of the glucocorticoid receptor (GR). W...

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Detalles Bibliográficos
Autores principales: Garland, Michael A., Sengupta, Sumitra, Mathew, Lijoy K., Truong, Lisa, de Jong, Esther, Piersma, Aldert H., La Du, Jane, Tanguay, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584771/
https://www.ncbi.nlm.nih.gov/pubmed/31249786
http://dx.doi.org/10.1016/j.toxrep.2019.05.013