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Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens

The implementation of whole-genome sequencing in food safety has revolutionized foodborne pathogen tracking and outbreak investigations. The vast amounts of genomic data that are being produced through ongoing surveillance efforts continue advancing our understanding of pathogen diversity and genome...

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Autor principal: Kovac, Jasna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584884/
https://www.ncbi.nlm.nih.gov/pubmed/31186312
http://dx.doi.org/10.1128/mSystems.00164-19
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author Kovac, Jasna
author_facet Kovac, Jasna
author_sort Kovac, Jasna
collection PubMed
description The implementation of whole-genome sequencing in food safety has revolutionized foodborne pathogen tracking and outbreak investigations. The vast amounts of genomic data that are being produced through ongoing surveillance efforts continue advancing our understanding of pathogen diversity and genome biology. Produced genomic data are also supporting the use of metagenomics and metatranscriptomics for detection and functional characterization of microbiological hazards in foods and food processing environments. In addition to that, many studies have shown that metabolic and pathogenic potential, antimicrobial resistance, and other phenotypes relevant to food safety can be predicted from whole-genome sequences, omitting the need for multiple laboratory tests. Nevertheless, further work in the area of functional inference is necessary to enable accurate interpretation of functional information inferred from genomic and metagenomic data, as well as real-time detection and tracking of high-risk pathogen subtypes and microbiomes.
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spelling pubmed-65848842019-07-03 Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens Kovac, Jasna mSystems Perspective The implementation of whole-genome sequencing in food safety has revolutionized foodborne pathogen tracking and outbreak investigations. The vast amounts of genomic data that are being produced through ongoing surveillance efforts continue advancing our understanding of pathogen diversity and genome biology. Produced genomic data are also supporting the use of metagenomics and metatranscriptomics for detection and functional characterization of microbiological hazards in foods and food processing environments. In addition to that, many studies have shown that metabolic and pathogenic potential, antimicrobial resistance, and other phenotypes relevant to food safety can be predicted from whole-genome sequences, omitting the need for multiple laboratory tests. Nevertheless, further work in the area of functional inference is necessary to enable accurate interpretation of functional information inferred from genomic and metagenomic data, as well as real-time detection and tracking of high-risk pathogen subtypes and microbiomes. American Society for Microbiology 2019-06-11 /pmc/articles/PMC6584884/ /pubmed/31186312 http://dx.doi.org/10.1128/mSystems.00164-19 Text en Copyright © 2019 Kovac. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Perspective
Kovac, Jasna
Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens
title Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens
title_full Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens
title_fullStr Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens
title_full_unstemmed Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens
title_short Precision Food Safety: a Paradigm Shift in Detection and Control of Foodborne Pathogens
title_sort precision food safety: a paradigm shift in detection and control of foodborne pathogens
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584884/
https://www.ncbi.nlm.nih.gov/pubmed/31186312
http://dx.doi.org/10.1128/mSystems.00164-19
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