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Role of IDO and TDO in Cancers and Related Diseases and the Therapeutic Implications

Kynurenine (Kyn) pathway is a significant metabolic pathway of tryptophan (Trp). The metabolites of the Kyn pathway are closely correlated with numerous diseases. Two main enzymes, indoleamine-2,3-dioxygenase (IDO) and tryptophan-2,3-dioxygenase (TDO or TDO2), regulate the first and rate-limiting st...

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Detalles Bibliográficos
Autores principales:	Ye, Zixiang, Yue, Linxiu, Shi, Jiachen, Shao, Mingmei, Wu, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584917/ https://www.ncbi.nlm.nih.gov/pubmed/31258785 http://dx.doi.org/10.7150/jca.31727

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