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Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway

BACKGROUND: Oxymatrine (OM), a quinolizidine alkaloid extracted from a herb Sophorae Flavescentis Radix, has been used to treat liver fibrotic diseases. However, the mechanism of its anti-fibrosis effects is still unclear. TGF-β/Smad signaling and miR-195 have been proved to paly an important role i...

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Detalles Bibliográficos
Autores principales:	Song, Li-Ying, Ma, Yu-Tao, Fang, Wei-Jin, He, Yang, Wu, Jia-Li, Zuo, Shan-Ru, Deng, Zhen-Zhen, Wang, Sheng-Feng, Liu, Shi-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585021/ https://www.ncbi.nlm.nih.gov/pubmed/31221141 http://dx.doi.org/10.1186/s12906-019-2560-2

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