Cargando…
Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach
Personalized care of cancer patients undergoing treatment with immune checkpoint inhibitors will require approaches that can predict their susceptibility to immune-related adverse events. Understanding the role of germline genetic factors in determining individual responses to immunotherapy will dee...
Autores principales: | Khan, Zia, Hammer, Christian, Guardino, Ellie, Chandler, G. Scott, Albert, Matthew L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585053/ https://www.ncbi.nlm.nih.gov/pubmed/31221204 http://dx.doi.org/10.1186/s13073-019-0652-8 |
Ejemplares similares
-
Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer
por: Khan, Zia, et al.
Publicado: (2020) -
Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade
por: Khan, Zia, et al.
Publicado: (2021) -
Proton pump inhibitors and adverse kidney outcomes during immune checkpoint blockade: time to sound the alarm?
por: Tan, Hui Zhuan, et al.
Publicado: (2023) -
Immune-related adverse events and the balancing act of immunotherapy
por: Conroy, Michael, et al.
Publicado: (2022) -
Uncoupling Therapeutic Efficacy from Immune-Related Adverse Events in Immune Checkpoint Blockade
por: Hu, Weilei, et al.
Publicado: (2020)