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PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cells

BACKGROUND: In order to prepare the genome for gametogenesis, primordial germ cells (PGCs) undergo extensive epigenetic reprogramming during migration toward the gonads in mammalian embryos. This includes changes on a genome-wide scale and additionally in females the remodeling of the inactive X-chr...

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Detalles Bibliográficos
Autores principales:	Mallol, Anna, Guirola, Maria, Payer, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585054/ https://www.ncbi.nlm.nih.gov/pubmed/31221220 http://dx.doi.org/10.1186/s13072-019-0284-7

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