DNA methylation signature of human hippocampus in Alzheimer’s disease is linked to neurogenesis

BACKGROUND: Drawing the epigenome landscape of Alzheimer’s disease (AD) still remains a challenge. To characterize the epigenetic molecular basis of the human hippocampus in AD, we profiled genome-wide DNA methylation levels in hippocampal samples from a cohort of pure AD patients and controls by us...

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Detalles Bibliográficos
Autores principales: Altuna, Miren, Urdánoz-Casado, Amaya, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María V., Labarga, Alberto, Lepesant, Julie M. J., Roldán, Miren, Blanco-Luquin, Idoia, Perdones, Álvaro, Larumbe, Rosa, Jericó, Ivonne, Echavarri, Carmen, Méndez-López, Iván, Di Stefano, Luisa, Mendioroz, Maite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585076/
https://www.ncbi.nlm.nih.gov/pubmed/31217032
http://dx.doi.org/10.1186/s13148-019-0672-7

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