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A comprehensive analysis of NPHS1 gene mutations in patients with sporadic focal segmental glomerulosclerosis
BACKGROUND: Focal segmental glomerulosclerosis (FSGS) is still one of the common causes of refractory nephrotic syndrome. Nephrin, encoded by podocyte-specific NPHS1 gene, participated in the pathogenesis of FSGS. The sites of NPHS1 mutations in FSGS is not clarified very well. In this study, we inv...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585123/ https://www.ncbi.nlm.nih.gov/pubmed/31216994 http://dx.doi.org/10.1186/s12881-019-0845-4 |