Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

OBJECTIVES: Idiopathic inflammatory myopathies (IIM) are a spectrum of rare autoimmune diseases characterised clinically by muscle weakness and heterogeneous systemic organ involvement. The strongest genetic risk is within the major histocompatibility complex (MHC). Since autoantibody presence defin...

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Detalles Bibliográficos
Autores principales: Rothwell, Simon, Chinoy, Hector, Lamb, Janine A, Miller, Frederick W, Rider, Lisa G, Wedderburn, Lucy R, McHugh, Neil J, Mammen, Andrew L, Betteridge, Zoe E, Tansley, Sarah L, Bowes, John, Vencovský, Jiří, Deakin, Claire T, Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M, Reed, Ann M, Molberg, Øyvind, Benveniste, Olivier, Mathiesen, Pernille R, Radstake, Timothy R D J, Doria, Andrea, de Bleecker, Jan, Lee, Annette T, Hanna, Michael G, Machado, Pedro M, Ollier, William E, Gregersen, Peter K, Padyukov, Leonid, O'Hanlon, Terrance P, Cooper, Robert G, Lundberg, Ingrid E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Myositis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585280/
https://www.ncbi.nlm.nih.gov/pubmed/31138531
http://dx.doi.org/10.1136/annrheumdis-2019-215046

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