Second round results from the Manchester ‘Lung Health Check’ community-based targeted lung cancer screening pilot

We report results from the second annual screening round (T1) of Manchester’s ‘Lung Health Check’ pilot of community-based lung cancer screening in deprived areas (undertaken June to August 2017). Screening adherence was 90% (n=1194/1323): 92% of CT scans were classified negative, 6% indeterminate a...

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Detalles Bibliográficos
Autores principales: Crosbie, Phil A, Balata, Haval, Evison, Matthew, Atack, Melanie, Bayliss-Brideaux, Val, Colligan, Denis, Duerden, Rebecca, Eaglesfield, Josephine, Edwards, Timothy, Elton, Peter, Foster, Julie, Greaves, Melanie, Hayler, Graham, Higgins, Coral, Howells, John, Irion, Klaus, Karunaratne, Devinda, Kelly, Jodie, King, Zoe, Lyons, Judith, Manson, Sarah, Mellor, Stuart, Miller, Donna, Myerscough, Amanda, Newton, Tom, O’Leary, Michelle, Pearson, Rachel, Pickford, Julie, Sawyer, Richard, Screaton, Nick J, Sharman, Anna, Simmons, Maggi, Smith, Elaine, Taylor, Ben, Taylor, Sarah, Walsham, Anna, Watts, Angela, Whittaker, James, Yarnell, Laura, Threlfall, Anthony, Barber, Phil V, Tonge, Janet, Booton, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585285/
https://www.ncbi.nlm.nih.gov/pubmed/30420406
http://dx.doi.org/10.1136/thoraxjnl-2018-212547
Descripción
Sumario:We report results from the second annual screening round (T1) of Manchester’s ‘Lung Health Check’ pilot of community-based lung cancer screening in deprived areas (undertaken June to August 2017). Screening adherence was 90% (n=1194/1323): 92% of CT scans were classified negative, 6% indeterminate and 2.5% positive; there were no interval cancers. Lung cancer incidence was 1.6% (n=19), 79% stage I, treatments included surgery (42%, n=9), stereotactic ablative radiotherapy (26%, n=5) and radical radiotherapy (5%, n=1). False-positive rate was 34.5% (n=10/29), representing 0.8% of T1 participants (n=10/1194). Targeted community-based lung cancer screening promotes high screening adherence and detects high rates of early stage lung cancer.

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