Gas6 Attenuates Sepsis-Induced Tight Junction Injury and Vascular Endothelial Hyperpermeability via the Axl/NF-κB Signaling Pathway

Vascular endothelial functional dysregulation and barrier disruption are involved the initiation and development of sepsis. Growth arrest-specific protein 6 (Gas6), one of the endogenous ligands of TAM receptors (Tyro3, Axl, and Mertk), is confirmed to have beneficial functions in hemostasis, inflam...

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Detalles Bibliográficos
Autores principales: Ni, Jingjing, Lin, Miaotong, Jin, Yangjie, Li, Jiajia, Guo, Yayong, Zhou, Jindong, Hong, Guangliang, Zhao, Guangju, Lu, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585310/
https://www.ncbi.nlm.nih.gov/pubmed/31263416
http://dx.doi.org/10.3389/fphar.2019.00662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585310/
https://www.ncbi.nlm.nih.gov/pubmed/31263416
http://dx.doi.org/10.3389/fphar.2019.00662

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