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Studies on the treatment of melanoma with folate acid conjugated dextran and lauryl alcohol loaded with IMD0354

Background: IMD-0354 is a kind of hydrophobic small molecule inhibitor of IKKβ, which can effectively inhibit the NF-κB pathway. Besides, IMD-0354 can inhibit a variety of tumor cells in culture, but its poor water solubility and low utilization have limited its clinical application. Methods: In thi...

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Detalles Bibliográficos
Autores principales:	Liu, Can, Chen, Wei, Chen, Zizi, Yan, Yu, Wang, Qing, Xie, Huiqing, Chen, Xiang, Wang, Aijun, Tang, Shijie, Zhou, Jianda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585409/ https://www.ncbi.nlm.nih.gov/pubmed/31354298 http://dx.doi.org/10.2147/OTT.S207685

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