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Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import

Human immunodeficiency virus (HIV) continues to be a major contributor to morbidity and mortality worldwide, particularly in developing nations where high cost and logistical issues severely limit the use of current HIV therapeutics. This, combined HIV's high propensity to develop resistance, m...

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Detalles Bibliográficos
Autores principales: Wagstaff, Kylie M., Headey, Stephen, Telwatte, Sushama, Tyssen, David, Hearps, Anna C., Thomas, David R., Tachedjian, Gilda, Jans, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585680/
https://www.ncbi.nlm.nih.gov/pubmed/30216959
http://dx.doi.org/10.1111/cmi.12953

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