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Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis

AIMS: To describe the prevalence of major cardiovascular disease (CVD) and risk factor control in a contemporary population with Type 2 diabetes. METHODS: We used data from the national registry in Scotland, Scottish Care Information‐Diabetes, linked to hospital admissions. Using descriptive statist...

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Autores principales: McGurnaghan, S., Blackbourn, L. A. K., Mocevic, E., Haagen Panton, U., McCrimmon, R. J., Sattar, N., Wild, S., Colhoun, H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585697/
https://www.ncbi.nlm.nih.gov/pubmed/30246473
http://dx.doi.org/10.1111/dme.13825
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author McGurnaghan, S.
Blackbourn, L. A. K.
Mocevic, E.
Haagen Panton, U.
McCrimmon, R. J.
Sattar, N.
Wild, S.
Colhoun, H. M.
author_facet McGurnaghan, S.
Blackbourn, L. A. K.
Mocevic, E.
Haagen Panton, U.
McCrimmon, R. J.
Sattar, N.
Wild, S.
Colhoun, H. M.
author_sort McGurnaghan, S.
collection PubMed
description AIMS: To describe the prevalence of major cardiovascular disease (CVD) and risk factor control in a contemporary population with Type 2 diabetes. METHODS: We used data from the national registry in Scotland, Scottish Care Information‐Diabetes, linked to hospital admissions. Using descriptive statistics and logistic regression we described associations of risk factors with CVD. CVD was defined based on diagnostic codes in primary or secondary care data for ischaemic heart disease, cerebrovascular disease peripheral arterial disease, heart failure, cardiac arrhythmia, hypertensive heart disease and revascularization procedures. RESULTS: Among 248 400 people with Type 2 diabetes with a median age of 67.5 years (IQR 58.2, 76.1) and median diabetes duration of 7.8 years (3.8, 13.0), 32% had prior CVD (35% of men, 29% of women). Median HbA(1c) overall was 55 mmol/mol (7.2%), median SBP was 132 mmHg, median total cholesterol was 4.1 mmol/l and mean BMI was 32 kg/m(2) (.) Overall two‐thirds (65% of men, 68% of women) have two or more of the following CVD risk factor thresholds: HbA(1c) ≥ 53 mmol/mol (7%), SBP > 130 mmHg or DBP > 80 mmHg, total cholesterol ≥ 5 mmol/l or BMI ≥ 30 kg/m(2), or were currently smoking. Overall 84% were taking anti‐hypertensives and 75% a statin. Use of metformin was common at 58%, but other diabetes drugs that reduce CVD were rarely used. CONCLUSIONS: There continues to be a high prevalence of CVD among people with Type 2 diabetes and a high level of unmet need for risk factor control. This implies substantial scope for reducing the excess risk of CVD in diabetes through improved management of known risk factors.
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spelling pubmed-65856972019-06-27 Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis McGurnaghan, S. Blackbourn, L. A. K. Mocevic, E. Haagen Panton, U. McCrimmon, R. J. Sattar, N. Wild, S. Colhoun, H. M. Diabet Med Research Articles AIMS: To describe the prevalence of major cardiovascular disease (CVD) and risk factor control in a contemporary population with Type 2 diabetes. METHODS: We used data from the national registry in Scotland, Scottish Care Information‐Diabetes, linked to hospital admissions. Using descriptive statistics and logistic regression we described associations of risk factors with CVD. CVD was defined based on diagnostic codes in primary or secondary care data for ischaemic heart disease, cerebrovascular disease peripheral arterial disease, heart failure, cardiac arrhythmia, hypertensive heart disease and revascularization procedures. RESULTS: Among 248 400 people with Type 2 diabetes with a median age of 67.5 years (IQR 58.2, 76.1) and median diabetes duration of 7.8 years (3.8, 13.0), 32% had prior CVD (35% of men, 29% of women). Median HbA(1c) overall was 55 mmol/mol (7.2%), median SBP was 132 mmHg, median total cholesterol was 4.1 mmol/l and mean BMI was 32 kg/m(2) (.) Overall two‐thirds (65% of men, 68% of women) have two or more of the following CVD risk factor thresholds: HbA(1c) ≥ 53 mmol/mol (7%), SBP > 130 mmHg or DBP > 80 mmHg, total cholesterol ≥ 5 mmol/l or BMI ≥ 30 kg/m(2), or were currently smoking. Overall 84% were taking anti‐hypertensives and 75% a statin. Use of metformin was common at 58%, but other diabetes drugs that reduce CVD were rarely used. CONCLUSIONS: There continues to be a high prevalence of CVD among people with Type 2 diabetes and a high level of unmet need for risk factor control. This implies substantial scope for reducing the excess risk of CVD in diabetes through improved management of known risk factors. John Wiley and Sons Inc. 2018-10-10 2019-06 /pmc/articles/PMC6585697/ /pubmed/30246473 http://dx.doi.org/10.1111/dme.13825 Text en © 2018 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
McGurnaghan, S.
Blackbourn, L. A. K.
Mocevic, E.
Haagen Panton, U.
McCrimmon, R. J.
Sattar, N.
Wild, S.
Colhoun, H. M.
Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis
title Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis
title_full Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis
title_fullStr Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis
title_full_unstemmed Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis
title_short Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis
title_sort cardiovascular disease prevalence and risk factor prevalence in type 2 diabetes: a contemporary analysis
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585697/
https://www.ncbi.nlm.nih.gov/pubmed/30246473
http://dx.doi.org/10.1111/dme.13825
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