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High molecular weight hyaluronan protects cartilage from degradation by inhibiting aggrecanase expression

Hyaluronan (HA) is an extracellular matrix (ECM) component of articular cartilage and has been used to treat patients with osteoarthritis (OA). A disintegrin and metalloproteinases with thrombospondin motifs (ADAMTSs) play an important role in cartilage degradation in OA. We have previously reported...

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Detalles Bibliográficos
Autores principales:	Ohtsuki, Takashi, Asano, Keiichi, Inagaki, Junko, Shinaoka, Akira, Kumagishi‐Shinaoka, Kanae, Cilek, Mehmet Z., Hatipoglu, Omer F., Oohashi, Toshitaka, Nishida, Keiichiro, Komatsubara, Issei, Hirohata, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585799/ https://www.ncbi.nlm.nih.gov/pubmed/30117186 http://dx.doi.org/10.1002/jor.24126

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