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Implementation of deep neural networks to count dopamine neurons in substantia nigra

Unbiased estimates of neuron numbers within substantia nigra are crucial for experimental Parkinson's disease models and gene‐function studies. Unbiased stereological counting techniques with optical fractionation are successfully implemented, but are extremely laborious and time‐consuming. The...

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Detalles Bibliográficos
Autores principales: Penttinen, Anna‐Maija, Parkkinen, Ilmari, Blom, Sami, Kopra, Jaakko, Andressoo, Jaan‐Olle, Pitkänen, Kari, Voutilainen, Merja H., Saarma, Mart, Airavaara, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585833/
https://www.ncbi.nlm.nih.gov/pubmed/30144349
http://dx.doi.org/10.1111/ejn.14129