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Magnolin targeting of ERK1/2 inhibits cell proliferation and colony growth by induction of cellular senescence in ovarian cancer cells

Ras/Raf/MEKs/ERKs and PI3 K/Akt/mTOR signaling pathways have key roles in cancer development and growth processes, as well as in cancer malignance and chemoresistance. In this study, we screened the therapeutic potential of magnolin using 15 human cancer cell lines and combined magnolin sensitivity...

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Detalles Bibliográficos
Autores principales:	Song, Ji‐Hong, Lee, Cheol‐Jung, An, Hyun‐Jung, Yoo, Sun‐Mi, Kang, Han C., Lee, Joo Y., Kim, Kwang D., Kim, Dae J., Lee, Hye S., Cho, Yong‐Yeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585859/ https://www.ncbi.nlm.nih.gov/pubmed/30230030 http://dx.doi.org/10.1002/mc.22909

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