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Normal Calcium-Activated Anion Secretion in a Mouse Selectively Lacking TMEM16A in Intestinal Epithelium
Calcium-activated anion secretion is expected to ameliorate cystic fibrosis, a genetic disease that carries an anion secretory defect in exocrine tissues. Human patients and animal models of the disease that present a mild intestinal phenotype have been postulated to bear a compensatory calcium-acti...
Autores principales: | Vega, Génesis, Guequén, Anita, Johansson, Malin E. V., Arike, Liisa, Martínez-Abad, Beatriz, Nyström, Elisabeth E. L., Scudieri, Paolo, Pedemonte, Nicoletta, Millar-Büchner, Pamela, Philp, Amber R., Galietta, Luis J., Hansson, Gunnar C., Flores, Carlos A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585864/ https://www.ncbi.nlm.nih.gov/pubmed/31263421 http://dx.doi.org/10.3389/fphys.2019.00694 |
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