Cargando…
Structural determinants and genetic modifications enhance BMP2 stability and extracellular secretion
The short half‐life and use of recombinant bone morphogenetic protein (BMP)2 in large doses poses major limitations in the clinic. Events regulating posttranslational processing and degradation of BMP2 in situ, linked to its secretion, have not been understood. Toward identifying mechanisms regulati...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586023/ https://www.ncbi.nlm.nih.gov/pubmed/31225515 http://dx.doi.org/10.1096/fba.2018-00023 |