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The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a lethal neuromuscular disorder caused by loss of dystrophin. Several therapeutic modalities are currently in clinical trials but none will achieve maximum functional rescue and full disease correction. Therefore, we explored the potential of combining the benefi...

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Detalles Bibliográficos
Autores principales:	Guiraud, Simon, Edwards, Benjamin, Babbs, Arran, Squire, Sarah E, Berg, Adam, Moir, Lee, Wood, Matthew J, Davies, Kay E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586144/ https://www.ncbi.nlm.nih.gov/pubmed/30990876 http://dx.doi.org/10.1093/hmg/ddz049

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