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Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice
Aquaporin-4 (AQP4) plays an important role in regulating water exchange across the blood-brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice (AQP4-KO) have reported considerable protection from brain edema induced by acute water intoxication and ischemic strok...
Autores principales: | Zhang, Yifan, Xu, Kui, Liu, Yuchi, Erokwu, Bernadette O., Zhao, Pan, Flask, Chris A., Ramos-Estebanez, Ciro, Farr, George W., LaManna, Joseph C., Boron, Walter F., Yu, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586297/ https://www.ncbi.nlm.nih.gov/pubmed/31220136 http://dx.doi.org/10.1371/journal.pone.0218415 |
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