Blowing epithelial cell bubbles with GumB: ShlA-family pore-forming toxins induce blebbing and rapid cellular death in corneal epithelial cells

Medical devices, such as contact lenses, bring bacteria in direct contact with human cells. Consequences of these host-pathogen interactions include the alteration of mammalian cell surface architecture and induction of cellular death that renders tissues more susceptible to infection. Gram-negative...

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Detalles Bibliográficos
Autores principales: Brothers, Kimberly M., Callaghan, Jake D., Stella, Nicholas A., Bachinsky, Julianna M., AlHigaylan, Mohammed, Lehner, Kara L., Franks, Jonathan M., Lathrop, Kira L., Collins, Elliot, Schmitt, Deanna M., Horzempa, Joseph, Shanks, Robert M. Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586354/
https://www.ncbi.nlm.nih.gov/pubmed/31220184
http://dx.doi.org/10.1371/journal.ppat.1007825

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