The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults but can cause invasive disease, such as meningitis, in the newborn. To gain access to the central nervous system, GBS must interact with and penetrate brain or meningeal blood vessels; however, the exact mechanis...

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Detalles Bibliográficos
Autores principales: Deng, Liwen, Spencer, Brady L., Holmes, Joshua A., Mu, Rong, Rego, Sara, Weston, Thomas A., Hu, Yoonsung, Sanches, Glenda F., Yoon, Sunghyun, Park, Nogi, Nagao, Prescilla E., Jenkinson, Howard F., Thornton, Justin A., Seo, Keun Seok, Nobbs, Angela H., Doran, Kelly S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586375/
https://www.ncbi.nlm.nih.gov/pubmed/31181121
http://dx.doi.org/10.1371/journal.ppat.1007848

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