Data on SVCT2 transporter expression and localization in cancer cell lines and tissues

The data presented in this article are related to the research paper entitled “Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer”, available in Free Radical Biology and Medicine Journal [1]. In this article, we examined...

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Detalles Bibliográficos
Autores principales: Roa, Francisco J., Peña, Eduardo, Inostroza, Eveling, Sotomayor, Kirsty, González, Mauricio, Gutierrez-Castro, Francisco A., Maurin, Michelle, Sweet, Karen, Labrousse, Claire, Gatica, Marcell, Aylwin, Carlos F., Mendoza, Pamela, Maldonado, Mafalda, Delgado, Carolina, Madariaga, Jaime, Panes, Jessica, Silva-Grecchi, Tiare, Concha, Ilona I., Moraga-Cid, Gustavo, Reyes, Alejandro M., Muñoz-Montesino, Carola, Vera, Juan Carlos, Rivas, Coralia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586595/
https://www.ncbi.nlm.nih.gov/pubmed/31249848
http://dx.doi.org/10.1016/j.dib.2019.103972
Descripción
Sumario:The data presented in this article are related to the research paper entitled “Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer”, available in Free Radical Biology and Medicine Journal [1]. In this article, we examined the SVCT2 transporter expression in various breast cancer cell lines using RT-PCR and Western blot assays. In addition, we analyzed the subcellular localization of SVCT2 by immunofluorescence colocalization assays and cellular fractionation experiments. Finally, an analysis of different cancer tissue microarrays immunostained for SVCT2 and imaged by The Human Protein Atlas (https://www.proteinatlas.org) is presented.

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