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Frequency of the CYP2C19*17 polymorphism in a Chilean population and its effect on voriconazole plasma concentration in immunocompromised children

Invasive fungal infections (IFIs) are the most frequent cause of morbidity and mortality in immunocompromised children. Voriconazole is the first-line antifungal choice in the treatment of IFIs like aspergillosis. Voriconazole pharmacokinetics vary widely among patients and voriconazole is metaboliz...

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Detalles Bibliográficos
Autores principales:	Espinoza, N., Galdames, J., Navea, D., Farfán, M. J., Salas, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586657/ https://www.ncbi.nlm.nih.gov/pubmed/31222084 http://dx.doi.org/10.1038/s41598-019-45345-2

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