A MiSeq-HyDRA platform for enhanced HIV drug resistance genotyping and surveillance

Conventional HIV drug resistance (HIVDR) genotyping utilizes Sanger sequencing (SS) methods, which are limited by low data throughput and the inability of detecting low abundant drug resistant variants (LADRVs). Here we present a next generation sequencing (NGS)-based HIVDR typing platform that leve...

Descripción completa

Detalles Bibliográficos
Autores principales: Taylor, Tracy, Lee, Emma R., Nykoluk, Mikaela, Enns, Eric, Liang, Binhua, Capina, Rupert, Gauthier, Marie-Krystel, Domselaar, Gary Van, Sandstrom, Paul, Brooks, James, Ji, Hezhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586679/
https://www.ncbi.nlm.nih.gov/pubmed/31222149
http://dx.doi.org/10.1038/s41598-019-45328-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586679/
https://www.ncbi.nlm.nih.gov/pubmed/31222149
http://dx.doi.org/10.1038/s41598-019-45328-3

Ejemplares similares