Mesenchymal Stem Cell Therapy for Doxorubicin-Induced Cardiomyopathy: Potential Mechanisms, Governing Factors, and Implications of the Heart Stem Cell Debate

Over the past decades, researchers have reported several mechanisms for doxorubicin (DOX)-induced cardiomyopathy, including oxidative stress, inflammation, and apoptosis. Another mechanism that has been suggested is that DOX interferes with the cell cycle and induces oxidative stress in C-kit+ cells...

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Detalles Bibliográficos
Autores principales: Abushouk, Abdelrahman Ibrahim, Salem, Amr Muhammad Abdo, Saad, Anas, Afifi, Ahmed M., Afify, Abdelrahman Yousry, Afify, Hesham, Salem, Hazem S.E., Ghanem, Esraa, Abdel-Daim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586740/
https://www.ncbi.nlm.nih.gov/pubmed/31258475
http://dx.doi.org/10.3389/fphar.2019.00635

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