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Microglia-derived TNF-α mediates endothelial necroptosis aggravating blood brain–barrier disruption after ischemic stroke

Endothelium (EC) is a key component of blood–brain barrier (BBB), and has an important position in the neurovascular unit. Its dysfunction and death after cerebral ischemic/reperfusion (I/R) injury not only promote evolution of neuroinflammation and brain edema, but also increase the risk of intrace...

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Detalles Bibliográficos
Autores principales:	Chen, An-Qi, Fang, Zhi, Chen, Xiao-Lu, Yang, Shuai, Zhou, Yi-Fan, Mao, Ling, Xia, Yuan-Peng, Jin, Hui-Juan, Li, Ya-Nan, You, Ming-Feng, Wang, Xu-Xia, Lei, Hao, He, Quan-Wei, Hu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586814/ https://www.ncbi.nlm.nih.gov/pubmed/31221990 http://dx.doi.org/10.1038/s41419-019-1716-9

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