Combating viral contaminants in CHO cells by engineering innate immunity

Viral contamination in biopharmaceutical manufacturing can lead to shortages in the supply of critical therapeutics. To facilitate the protection of bioprocesses, we explored the basis for the susceptibility of CHO cells to RNA virus infection. Upon infection with certain ssRNA and dsRNA viruses, CH...

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Detalles Bibliográficos
Autores principales: Chiang, Austin W. T., Li, Shangzhong, Kellman, Benjamin P., Chattopadhyay, Gouri, Zhang, Yaqin, Kuo, Chih-Chung, Gutierrez, Jahir M., Ghazi, Faezeh, Schmeisser, Hana, Ménard, Patrice, Bjørn, Sara Petersen, Voldborg, Bjørn G., Rosenberg, Amy S., Puig, Montserrat, Lewis, Nathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586939/
https://www.ncbi.nlm.nih.gov/pubmed/31222165
http://dx.doi.org/10.1038/s41598-019-45126-x

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