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Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
Cutaneous leishmaniasis (CL) is the most common leishmaniasis syndrome, yet a neglected disease in industrialized non-endemic countries, where it has become an emergent problem. The lack of clinical experience, evidence-based literature and availability of some treatments complicates its management....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587016/ https://www.ncbi.nlm.nih.gov/pubmed/31275804 http://dx.doi.org/10.1016/j.idcr.2019.e00570 |
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author | Vasconcelos, Joana Torres, João Granado, Joana Baptista, Teresa Mansinho, Kamal |
author_facet | Vasconcelos, Joana Torres, João Granado, Joana Baptista, Teresa Mansinho, Kamal |
author_sort | Vasconcelos, Joana |
collection | PubMed |
description | Cutaneous leishmaniasis (CL) is the most common leishmaniasis syndrome, yet a neglected disease in industrialized non-endemic countries, where it has become an emergent problem. The lack of clinical experience, evidence-based literature and availability of some treatments complicates its management. We report a CL case in a 30 year-old man returned from Brazil, with a cutaneous ulcerated lesion, where it was possible to isolate Leishmania braziliensis/guyanensis complex (subgenus Viannia). An initial course of treatment with miltefosine was attempted, but considering the lack of response, liposomal amphotericin B was used, with very good results. Our report highlights the obstacles faced in the diagnosis and treatment of New World CL in non-endemic countries and the need for more funding and research. |
format | Online Article Text |
id | pubmed-6587016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-65870162019-07-02 Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem Vasconcelos, Joana Torres, João Granado, Joana Baptista, Teresa Mansinho, Kamal IDCases Article Cutaneous leishmaniasis (CL) is the most common leishmaniasis syndrome, yet a neglected disease in industrialized non-endemic countries, where it has become an emergent problem. The lack of clinical experience, evidence-based literature and availability of some treatments complicates its management. We report a CL case in a 30 year-old man returned from Brazil, with a cutaneous ulcerated lesion, where it was possible to isolate Leishmania braziliensis/guyanensis complex (subgenus Viannia). An initial course of treatment with miltefosine was attempted, but considering the lack of response, liposomal amphotericin B was used, with very good results. Our report highlights the obstacles faced in the diagnosis and treatment of New World CL in non-endemic countries and the need for more funding and research. Elsevier 2019-06-11 /pmc/articles/PMC6587016/ /pubmed/31275804 http://dx.doi.org/10.1016/j.idcr.2019.e00570 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Vasconcelos, Joana Torres, João Granado, Joana Baptista, Teresa Mansinho, Kamal Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem |
title | Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem |
title_full | Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem |
title_fullStr | Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem |
title_full_unstemmed | Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem |
title_short | Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem |
title_sort | cutaneous leishmaniasis in non-endemic countries: an emerging yet neglected problem |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587016/ https://www.ncbi.nlm.nih.gov/pubmed/31275804 http://dx.doi.org/10.1016/j.idcr.2019.e00570 |
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