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Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem

Cutaneous leishmaniasis (CL) is the most common leishmaniasis syndrome, yet a neglected disease in industrialized non-endemic countries, where it has become an emergent problem. The lack of clinical experience, evidence-based literature and availability of some treatments complicates its management....

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Detalles Bibliográficos
Autores principales: Vasconcelos, Joana, Torres, João, Granado, Joana, Baptista, Teresa, Mansinho, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587016/
https://www.ncbi.nlm.nih.gov/pubmed/31275804
http://dx.doi.org/10.1016/j.idcr.2019.e00570
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author Vasconcelos, Joana
Torres, João
Granado, Joana
Baptista, Teresa
Mansinho, Kamal
author_facet Vasconcelos, Joana
Torres, João
Granado, Joana
Baptista, Teresa
Mansinho, Kamal
author_sort Vasconcelos, Joana
collection PubMed
description Cutaneous leishmaniasis (CL) is the most common leishmaniasis syndrome, yet a neglected disease in industrialized non-endemic countries, where it has become an emergent problem. The lack of clinical experience, evidence-based literature and availability of some treatments complicates its management. We report a CL case in a 30 year-old man returned from Brazil, with a cutaneous ulcerated lesion, where it was possible to isolate Leishmania braziliensis/guyanensis complex (subgenus Viannia). An initial course of treatment with miltefosine was attempted, but considering the lack of response, liposomal amphotericin B was used, with very good results. Our report highlights the obstacles faced in the diagnosis and treatment of New World CL in non-endemic countries and the need for more funding and research.
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spelling pubmed-65870162019-07-02 Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem Vasconcelos, Joana Torres, João Granado, Joana Baptista, Teresa Mansinho, Kamal IDCases Article Cutaneous leishmaniasis (CL) is the most common leishmaniasis syndrome, yet a neglected disease in industrialized non-endemic countries, where it has become an emergent problem. The lack of clinical experience, evidence-based literature and availability of some treatments complicates its management. We report a CL case in a 30 year-old man returned from Brazil, with a cutaneous ulcerated lesion, where it was possible to isolate Leishmania braziliensis/guyanensis complex (subgenus Viannia). An initial course of treatment with miltefosine was attempted, but considering the lack of response, liposomal amphotericin B was used, with very good results. Our report highlights the obstacles faced in the diagnosis and treatment of New World CL in non-endemic countries and the need for more funding and research. Elsevier 2019-06-11 /pmc/articles/PMC6587016/ /pubmed/31275804 http://dx.doi.org/10.1016/j.idcr.2019.e00570 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Vasconcelos, Joana
Torres, João
Granado, Joana
Baptista, Teresa
Mansinho, Kamal
Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
title Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
title_full Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
title_fullStr Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
title_full_unstemmed Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
title_short Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
title_sort cutaneous leishmaniasis in non-endemic countries: an emerging yet neglected problem
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587016/
https://www.ncbi.nlm.nih.gov/pubmed/31275804
http://dx.doi.org/10.1016/j.idcr.2019.e00570
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