Imaging biomarkers in oncology: Basics and application to MRI

Cancer remains a global killer alongside cardiovascular disease. A better understanding of cancer biology has transformed its management with an increasing emphasis on a personalized approach, so‐called “precision cancer medicine.” Imaging has a key role to play in the management of cancer patients....

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Autores principales: Dregely, Isabel, Prezzi, Davide, Kelly‐Morland, Christian, Roccia, Elisa, Neji, Radhouene, Goh, Vicky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
CME Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587121/
https://www.ncbi.nlm.nih.gov/pubmed/29969192
http://dx.doi.org/10.1002/jmri.26058
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author Dregely, Isabel
Prezzi, Davide
Kelly‐Morland, Christian
Roccia, Elisa
Neji, Radhouene
Goh, Vicky
author_facet Dregely, Isabel
Prezzi, Davide
Kelly‐Morland, Christian
Roccia, Elisa
Neji, Radhouene
Goh, Vicky
author_sort Dregely, Isabel
collection PubMed
description Cancer remains a global killer alongside cardiovascular disease. A better understanding of cancer biology has transformed its management with an increasing emphasis on a personalized approach, so‐called “precision cancer medicine.” Imaging has a key role to play in the management of cancer patients. Imaging biomarkers that objectively inform on tumor biology, the tumor environment, and tumor changes in response to an intervention complement genomic and molecular diagnostics. In this review we describe the key principles for imaging biomarker development and discuss the current status with respect to magnetic resonance imaging (MRI). LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY: Stage 5 J. Magn. Reson. Imaging 2018;48:13–26.
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spelling pubmed-65871212019-07-02 Imaging biomarkers in oncology: Basics and application to MRI Dregely, Isabel Prezzi, Davide Kelly‐Morland, Christian Roccia, Elisa Neji, Radhouene Goh, Vicky J Magn Reson Imaging CME Article Cancer remains a global killer alongside cardiovascular disease. A better understanding of cancer biology has transformed its management with an increasing emphasis on a personalized approach, so‐called “precision cancer medicine.” Imaging has a key role to play in the management of cancer patients. Imaging biomarkers that objectively inform on tumor biology, the tumor environment, and tumor changes in response to an intervention complement genomic and molecular diagnostics. In this review we describe the key principles for imaging biomarker development and discuss the current status with respect to magnetic resonance imaging (MRI). LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY: Stage 5 J. Magn. Reson. Imaging 2018;48:13–26. John Wiley and Sons Inc. 2018-07-03 2018-07 /pmc/articles/PMC6587121/ /pubmed/29969192 http://dx.doi.org/10.1002/jmri.26058 Text en © 2018 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle CME Article
Dregely, Isabel
Prezzi, Davide
Kelly‐Morland, Christian
Roccia, Elisa
Neji, Radhouene
Goh, Vicky
Imaging biomarkers in oncology: Basics and application to MRI
title Imaging biomarkers in oncology: Basics and application to MRI
title_full Imaging biomarkers in oncology: Basics and application to MRI
title_fullStr Imaging biomarkers in oncology: Basics and application to MRI
title_full_unstemmed Imaging biomarkers in oncology: Basics and application to MRI
title_short Imaging biomarkers in oncology: Basics and application to MRI
title_sort imaging biomarkers in oncology: basics and application to mri
topic CME Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587121/
https://www.ncbi.nlm.nih.gov/pubmed/29969192
http://dx.doi.org/10.1002/jmri.26058
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