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CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms

CRISPR–Cas9–based genome editing has transformed the life sciences, enabling virtually unlimited genetic manipulation of genomes: The RNA-guided Cas9 endonuclease cuts DNA at a specific target sequence and the resulting double-strand breaks are mended by one of the intrinsic cellular repair pathways...

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Detalles Bibliográficos
Autores principales:	Brunner, Erich, Yagi, Ryohei, Debrunner, Marc, Beck-Schneider, Dezirae, Burger, Alexa, Escher, Eliane, Mosimann, Christian, Hausmann, George, Basler, Konrad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587125/ https://www.ncbi.nlm.nih.gov/pubmed/31196871 http://dx.doi.org/10.26508/lsa.201800267

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