Polo-Like Kinase 1 phosphorylates and stabilizes KLF4 to promote tumorigenesis in nasopharyngeal carcinoma

Rationale: Advanced nasopharyngeal carcinoma (NPC) is an aggressive disease with no targeted therapies and poor outcomes. New innovative targets are urgently needed. KLF4 has been extensively studied in the context of tumors, and current data suggest that it can act as either a tissue-specific tumor...

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Detalles Bibliográficos
Autores principales: Mai, Jia, Zhong, Zhuo-Yan, Guo, Gui-Fang, Chen, Xiu-Xing, Xiang, Yan-Qun, Li, Xuan, Zhang, Hai-Liang, Chen, Yu-Hong, Xu, Xue-Lian, Wu, Rui-Yan, Yu, Yan, Li, Zhi-Ling, Peng, Xiao-Dan, Huang, Yun, Zhou, Li-Huan, Feng, Gong-Kan, Guo, Xiang, Deng, Rong, Zhu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587166/
https://www.ncbi.nlm.nih.gov/pubmed/31281496
http://dx.doi.org/10.7150/thno.32908

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