Cargando…

The intervention mechanism of folic acid for benzo(a)pyrene toxic effects in vitro and in vivo

Folic acid is a necessary micronutrient for normal human growth and development. Benzo(a)pyrene (BaP) is a ubiquitously distributed environmental pollutant and its metabolite, benzo(a)pyrene-diol-epoxide, is known to exert a strong teratogenic and carcinogenic effect on the body’s tissues and cells....

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Pengcheng, Chen, Yuwei, Wang, Lei, Wu, Yang, Wang, Lichun, Wu, Yongning, Gong, Zhiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Research Papers: Carcinogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587224/ https://www.ncbi.nlm.nih.gov/pubmed/30020114 http://dx.doi.org/10.1097/CEJ.0000000000000461

Ejemplares similares

Targeting RNA helicase DHX33 blocks Ras‐driven lung tumorigenesis in vivo
por: Wang, Xingshun, et al.
Publicado: (2020)

LAMTOR1 degrades MHC-II via the endocytic in hepatocellular carcinoma
por: Wu, Bo, et al.
Publicado: (2022)

Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke
por: Wong, Ee Tsin, et al.
Publicado: (2020)

Hsa_circRNA_002144 promotes growth and metastasis of colorectal cancer through regulating miR-615-5p/LARP1/mTOR pathway
por: Wu, Mengqiong, et al.
Publicado: (2020)

The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro
por: Mascolo, Maria Grazia, et al.
Publicado: (2018)

Caprylic acid (C8:0) promotes bone metastasis of prostate cancer by dysregulated adipo‐osteogenic balance in bone marrow
por: Wang, Cuizhe, et al.
Publicado: (2020)

LINC02418 upregulates EPHA2 by competitively sponging miR-372-3p to promote 5-Fu/DDP chemoresistance in colorectal cancer
por: Yao, Fei, et al.
Publicado: (2022)

Ribosome assembly factor URB1 contributes to colorectal cancer proliferation through transcriptional activation of ATF4
por: Wang, Tao, et al.
Publicado: (2020)

AFF4 promotes tumorigenesis and tumor-initiation capacity of head and neck squamous cell carcinoma cells by regulating SOX2
por: Deng, Peng, et al.
Publicado: (2018)

Prolonged unfolded protein reaction is involved in the induction of chronic myeloid leukemia cell death upon oprozomib treatment
por: Wang, Fang, et al.
Publicado: (2020)

A yes-associated protein 1- Notch1 receptor positive feedback loop promotes breast cancer lung metastasis by attenuating the bone morphogenetic protein 4-SMAD family member 1/5 signaling
por: Zhao, Lin, et al.
Publicado: (2022)

LncRNA GAS5 regulates the Wnt/β-catenin pathway through the miR-18a-5p/AXIN2/GSK3β axis to inhibit the proliferation and migration of bladder cancer cells
por: Zhang, Ze, et al.
Publicado: (2022)

Knockdown of ISOC1 inhibits the proliferation and migration and induces the apoptosis of colon cancer cells through the AKT/GSK-3β pathway
por: Gao, Bo, et al.
Publicado: (2020)

De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes
por: Zhu, Jing, et al.
Publicado: (2013)

Interaction of SET domains with histones and nucleic acid structures in active chromatin
por: Krajewski, Wladyslaw A., et al.
Publicado: (2011)

Hypoxia‐inhibited miR‐338‐3p suppresses breast cancer progression by directly targeting ZEB2
por: He, Juanjuan, et al.
Publicado: (2020)

MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma
por: Wang, Wen, et al.
Publicado: (2012)

Ribose-5-phosphate isomerase A overexpression promotes liver cancer development in transgenic zebrafish via activation of ERK and β-catenin pathways
por: Chou, Yu-Ting, et al.
Publicado: (2019)

DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3
por: Zhang, Xue, et al.
Publicado: (2020)

The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity
por: Wang, Xiangfeng, et al.
Publicado: (2018)

Manual de métodos para la identificación de mutágenos y carcinógenos químicos ambientales
Publicado: (1980)

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis
por: Turovskaya, Olga, et al.
Publicado: (2008)

CpG methylation in exon 1 of transcription factor 4 increases with age in normal gastric mucosa and is associated with gene silencing in intestinal-type gastric cancers
por: Kim, Seung-Kyoon, et al.
Publicado: (2008)

Constitutive expression of human keratin 14 gene in mouse lung induces premalignant lesions and squamous differentiation
por: Habib Dakir, EL, et al.
Publicado: (2008)

Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17
por: Peychal, Stephanie E.-M., et al.
Publicado: (2009)

Epigenetic repression of E-cadherin by human papillomavirus 16 E7 protein
por: Laurson, Joanna, et al.
Publicado: (2010)

Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse
por: Matsumoto, Kojiro, et al.
Publicado: (2010)

Association between hMLH1 hypermethylation and JC virus (JCV) infection in human colorectal cancer (CRC)
por: Vilkin, Alex, et al.
Publicado: (2010)

Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women
por: Goodson, William H., et al.
Publicado: (2011)

Monocyclic aromatic amines as potential human carcinogens: old is new again
por: Skipper, Paul L., et al.
Publicado: (2010)

Both base excision repair and O(6)-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis
por: Wirtz, Stefan, et al.
Publicado: (2010)

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells
por: Thakur, Basant Kumar, et al.
Publicado: (2013)

Beneficial bacteria stimulate host immune cells to counteract dietary and genetic predisposition to mammary cancer in mice
por: Lakritz, Jessica R, et al.
Publicado: (2014)

Areca nut exposure increases secretion of tumor‐promoting cytokines in gingival fibroblasts that trigger DNA damage in oral keratinocytes
por: Illeperuma, Rasika P., et al.
Publicado: (2015)

Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment
por: Apostoli, Anthony J, et al.
Publicado: (2014)

Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells
por: Ji, Wei, et al.
Publicado: (2014)

Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3
por: Fetahu, Irfete S, et al.
Publicado: (2014)

Identification of cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers
por: Chudasama, Dimple, et al.
Publicado: (2018)

A novel experimental model for human mixed acinar–ductal pancreatic cancer
por: Doiron, Bruno, et al.
Publicado: (2018)

Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression
por: Dendo, Kasumi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pk8p1tgstfv3ke80a148ie3vp9