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Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions
The potential value of ultrahigh field (UHF) magnetic resonance imaging (MRI) and spectroscopy to biomedical research and in clinical applications drives the development of technologies to overcome its many challenges. The increased difficulties of imaging the human torso compared with the head incl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587233/ https://www.ncbi.nlm.nih.gov/pubmed/31188271 http://dx.doi.org/10.1097/RMR.0000000000000202 |
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author | Erturk, M. Arcan Li, Xiufeng Van de Moortele, Pierre-Fancois Ugurbil, Kamil Metzger, Gregory J. |
author_facet | Erturk, M. Arcan Li, Xiufeng Van de Moortele, Pierre-Fancois Ugurbil, Kamil Metzger, Gregory J. |
author_sort | Erturk, M. Arcan |
collection | PubMed |
description | The potential value of ultrahigh field (UHF) magnetic resonance imaging (MRI) and spectroscopy to biomedical research and in clinical applications drives the development of technologies to overcome its many challenges. The increased difficulties of imaging the human torso compared with the head include its overall size, the dimensions and location of its anatomic targets, the increased prevalence and magnitude of physiologic effects, the limited availability of tailored RF coils, and the necessary transmit chain hardware. Tackling these issues involves addressing notoriously inhomogeneous transmit B(1) (B(1)(+)) fields, limitations in peak B(1)(+), larger spatial variations of the static magnetic field B(0), and patient safety issues related to implants and local RF power deposition. However, as research institutions and vendors continue to innovate, the potential gains are beginning to be realized. Solutions overcoming the unique challenges associated with imaging the human torso are reviewed as are current studies capitalizing on the benefits of UHF in several anatomies and applications. As the field progresses, strategies associated with the RF system architecture, calibration methods, RF pulse optimization, and power monitoring need to be further integrated into the MRI systems making what are currently complex processes more streamlined. Meanwhile, the UHF MRI community must seize the opportunity to build upon what have been so far proof of principle and feasibility studies and begin to further explore the true impact in both research and the clinic. |
format | Online Article Text |
id | pubmed-6587233 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-65872332019-07-22 Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions Erturk, M. Arcan Li, Xiufeng Van de Moortele, Pierre-Fancois Ugurbil, Kamil Metzger, Gregory J. Top Magn Reson Imaging Review Articles The potential value of ultrahigh field (UHF) magnetic resonance imaging (MRI) and spectroscopy to biomedical research and in clinical applications drives the development of technologies to overcome its many challenges. The increased difficulties of imaging the human torso compared with the head include its overall size, the dimensions and location of its anatomic targets, the increased prevalence and magnitude of physiologic effects, the limited availability of tailored RF coils, and the necessary transmit chain hardware. Tackling these issues involves addressing notoriously inhomogeneous transmit B(1) (B(1)(+)) fields, limitations in peak B(1)(+), larger spatial variations of the static magnetic field B(0), and patient safety issues related to implants and local RF power deposition. However, as research institutions and vendors continue to innovate, the potential gains are beginning to be realized. Solutions overcoming the unique challenges associated with imaging the human torso are reviewed as are current studies capitalizing on the benefits of UHF in several anatomies and applications. As the field progresses, strategies associated with the RF system architecture, calibration methods, RF pulse optimization, and power monitoring need to be further integrated into the MRI systems making what are currently complex processes more streamlined. Meanwhile, the UHF MRI community must seize the opportunity to build upon what have been so far proof of principle and feasibility studies and begin to further explore the true impact in both research and the clinic. Lippincott Williams & Wilkins 2019-06 2019-06-11 /pmc/articles/PMC6587233/ /pubmed/31188271 http://dx.doi.org/10.1097/RMR.0000000000000202 Text en Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | Review Articles Erturk, M. Arcan Li, Xiufeng Van de Moortele, Pierre-Fancois Ugurbil, Kamil Metzger, Gregory J. Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions |
title | Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions |
title_full | Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions |
title_fullStr | Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions |
title_full_unstemmed | Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions |
title_short | Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions |
title_sort | evolution of uhf body imaging in the human torso at 7t: technology, applications, and future directions |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587233/ https://www.ncbi.nlm.nih.gov/pubmed/31188271 http://dx.doi.org/10.1097/RMR.0000000000000202 |
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