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A co-ultramicronized palmitoylethanolamide/luteolin composite mitigates clinical score and disease-relevant molecular markers in a mouse model of experimental autoimmune encephalomyelitis

BACKGROUND: Persistent and/or recurrent inflammatory processes are the main factor leading to multiple sclerosis (MS) lesions. The composite ultramicronized palmitoylethanolamide, an endogenous N-acylethanolamine, combined with the flavonoid luteolin, PEALut, have been found to exert neuroprotective...

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Detalles Bibliográficos
Autores principales: Contarini, Gabriella, Franceschini, Davide, Facci, Laura, Barbierato, Massimo, Giusti, Pietro, Zusso, Morena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587257/
https://www.ncbi.nlm.nih.gov/pubmed/31221190
http://dx.doi.org/10.1186/s12974-019-1514-4